Michael J Econs Selected Research

Osteopetrosis

6/2022	Unusual Cortical Phenotype After Hematopoietic Stem Cell Transplantation in a Patient With Osteopetrosis.
12/2021	Chloroquine increases osteoclast activity in vitro but does not improve the osteopetrotic bone phenotype of ADO2 mice.
1/2019	Interferon Gamma-1b Does Not Increase Markers of Bone Resorption in Autosomal Dominant Osteopetrosis.
9/2017	Osteopetroses, emphasizing potential approaches to treatment.
1/2017	Diagnosis and Management of Osteopetrosis: Consensus Guidelines From the Osteopetrosis Working Group.
12/2008	CLCN7 polymorphisms and bone mineral density in healthy premenopausal white women and in white men.
3/2007	Autosomal dominant osteopetrosis: clinical severity and natural history of 94 subjects with a chloride channel 7 gene mutation.
5/2004	Osteoclast-derived serum tartrate-resistant acid phosphatase 5b in Albers-Schonberg disease (type II autosomal dominant osteopetrosis).
8/2003	Chloride channel 7 (ClCN7) gene mutations and autosomal dominant osteopetrosis, type II.
8/2002	Sibling pair linkage and association studies between peak bone mineral density and the gene locus for the osteoclast-specific subunit (OC116) of the vacuolar proton pump on chromosome 11p12-13.

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Michael J Econs Research Topics

Disease

14	Hypophosphatemia 01/2020 - 04/2003
11	Osteopetrosis 06/2022 - 05/2002
9	Calcinosis 12/2018 - 04/2005
8	Familial Hypophosphatemic Rickets (X-Linked Hypophosphatemia) 03/2014 - 04/2003
8	Osteomalacia 02/2014 - 01/2004
7	Neoplasms (Cancer) 04/2019 - 04/2003
7	Hyperphosphatemia 10/2016 - 11/2006
7	Oncogenic osteomalacia 12/2009 - 04/2003
6	Autosomal Dominant Hypophosphatemic Rickets 01/2020 - 04/2003
6	Rickets (Rachitis) 02/2014 - 01/2004
4	Bone Resorption 12/2021 - 05/2004
4	Hyperostosis-hyperphosphatemia syndrome 12/2018 - 05/2007
3	Hypophosphatemic Rickets 01/2017 - 11/2009
3	Familial Hypophosphatemia (Phosphate Diabetes) 10/2016 - 04/2003
3	Hypercalciuria 02/2014 - 10/2006
3	Hereditary Hypophosphatemic Rickets with Hypercalciuria 02/2014 - 10/2006
3	Paraneoplastic Syndromes (Paraneoplastic Syndrome) 12/2009 - 01/2004
2	Familial Hyperphosphatemic Tumoral Calcinosis 12/2018 - 10/2014
2	Osteosclerosis 01/2017 - 06/2003
2	Multiple Fractures 01/2017 - 03/2005
1	Chronic Disease (Chronic Diseases) 01/2022
1	Bone Diseases (Bone Disease) 12/2021
1	Headache (Headaches) 01/2020
1	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 01/2020
1	Nausea 01/2020
1	Drug-Related Side Effects and Adverse Reactions 01/2020
1	Osteoporosis 04/2019
1	Body Weight (Weight, Body) 04/2019
1	Anemia 01/2017
1	Leukopenia 01/2017
1	Stomatognathic Diseases (Dental Disease) 01/2017
1	Camurati-Engelmann Syndrome (Progressive Diaphyseal Dysplasia) 10/2016
1	Calcinosis Cutis 10/2016
1	Heterotopic Ossification (Ectopic Ossification) 10/2016
1	Inflammation (Inflammations) 10/2016
1	Iron Deficiencies 05/2016
1	Hemochromatosis (Bronze Diabetes) 03/2016
1	Necrosis 02/2016
1	Enthesopathy 10/2015
1	Chronic Renal Insufficiency 09/2014
1	Hypocalcemia 08/2013
1	Male Infertility (Male Sterility) 12/2011
1	Nephrolithiasis 11/2009
1	Nephrocalcinosis 11/2009
1	Hypercalcemia (Milk Alkali Syndrome) 09/2007
1	Congenital Abnormalities (Deformity) 08/2007
1	Bone Marrow Failure Disorders 03/2007
1	Osteomyelitis 03/2007

Drug/Important Bio-Agent (IBA)

19	Phosphates (Orthophosphate)IBA 01/2020 - 04/2003
16	Fibroblast Growth Factor-23IBA 01/2020 - 04/2003
8	Calcitriol (Calcijex)FDA LinkGeneric 01/2020 - 04/2007
7	1,25-dihydroxyvitamin DIBA 02/2014 - 03/2005
6	Chloride Channels (Chloride Channel)IBA 12/2021 - 08/2003
6	IronIBA 01/2020 - 11/2011
6	Proteins (Proteins, Gene)FDA Link 01/2017 - 01/2004
5	Phosphorus (Red Phosphorus)IBA 01/2020 - 03/2005
5	Alkaline PhosphataseIBA 02/2016 - 06/2003
4	Parathyroid Hormone (Parathormone)IBA 01/2020 - 03/2005
4	Hormones (Hormone)IBA 01/2017 - 02/2012
3	MineralsIBA 01/2020 - 09/2007
3	Polypeptide N-acetylgalactosaminyltransferaseIBA 09/2007 - 04/2005
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2020 - 03/2012
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 05/2004
2	Messenger RNA (mRNA)IBA 02/2012 - 04/2003
2	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 12/2008 - 03/2007
2	GalactosamineIBA 09/2007 - 05/2007
2	Uridine Diphosphate (UDP)IBA 09/2007 - 05/2007
2	Tartrate-Resistant Acid PhosphataseIBA 05/2004 - 05/2002
2	EndopeptidasesIBA 01/2004 - 04/2003
1	Therapeutic UsesIBA 06/2022
1	desethylchloroquineIBA 12/2021
1	Ferritins (Ferritin)IBA 01/2020
1	Hemoglobins (Hemoglobin)IBA 01/2020
1	ferric derisomaltoseIBA 01/2020
1	iron isomaltoside 1000IBA 01/2020
1	ferric carboxymaltoseIBA 01/2020
1	Diphosphonates (Bisphosphonates)IBA 04/2019
1	GlucocorticoidsIBA 04/2019
1	Prednisolone (Predate)FDA LinkGeneric 04/2019
1	interferon gamma-1b FDA Link 01/2019
1	AutoantibodiesIBA 12/2018
1	CytokinesIBA 09/2017
1	RacivirIBA 10/2016
1	Interleukin-1 (Interleukin 1)IBA 10/2016
1	C-Reactive ProteinIBA 10/2016
1	Transferrin (beta 2 Transferrin)IBA 03/2016
1	NF-kappa B (NF-kB)IBA 02/2016
1	OsteocalcinIBA 02/2016
1	LigandsIBA 02/2016
1	OsteoprotegerinIBA 02/2016
1	hydroxide ionIBA 02/2014
1	Sodium-Phosphate Cotransporter Proteins (Sodium-Phosphate Cotransporter)IBA 11/2009
1	CalciumIBA 11/2009
1	Vitamin D FDA LinkGeneric 10/2008
1	Thymidine Monophosphate (TMP)IBA 11/2006
1	TransferasesIBA 11/2006
1	AcidsIBA 07/2006

Therapy/Procedure

6	Therapeutics 01/2022 - 01/2004
1	Hematopoietic Stem Cell Transplantation 06/2022
1	Immunomodulation 12/2018